How Letybo works
Letybo® is an FDA-approved prescription injectable for temporarily improving moderate to severe frown lines between the eyebrows in adults. It reduces activity in the muscles that create these lines, helping them appear softer. Treatment in other areas is off-label and requires an individual assessment.
How Letybo compares with Botox
Letybo and BOTOX® Cosmetic both use botulinum toxin type A to reduce muscle activity, but they are different medicines with different formulations. Letybo is approved for frown lines; BOTOX Cosmetic is also approved for forehead lines, crow’s feet, and platysma bands in adults. Their dosing units are not interchangeable. Your clinician can help you choose an appropriate option.
When changes appear and how long they last
Changes develop gradually and may begin within a few days. One clinical study found a median onset of three days. Results may last around three to four months, although timing varies. Letybo should not be administered more frequently than once every three months.
Important safety information
Boxed warning about Letybo toxin effects spreading beyond the injection area. Possible side effects include headache, injection-site reactions, eyelid drooping, dry eyes, and allergic reactions. Do not receive Letybo if you have an allergy to a botulinum toxin product or its ingredients, or an infection at a planned injection site. Tell your clinician about your medications, muscle or nerve conditions, swallowing or breathing problems, and pregnancy or breastfeeding.